In Mathemagician's Duel, players create "incanquations" from the cards in their hands to cast spells on their opponent, to reduce the opponent's Magical Strength to 0.

The incanquations are created by playing Magical Energy cards (numerals) and Magical Symbols cards (operators) so that when read left to right add up to the casting value of the chosen spell. Each spell when successfully cast, reduces the opponent's Magical Strength by a certain amount.

The game helps players practice mental math skills and working memory as they calculate the value of their own and their opponent's incanquations.